Unknown

Dataset Information

0

DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data.

ABSTRACT: With the decrease in costs, whole-exome sequencing (WES) has become a very popular and powerful tool for the identification of genetic variants underlying human diseases. However, integrated tools to precisely detect and systematically annotate copy number variations (CNVs) from WES data are still in great demand. Here, we present an online tool, DeAnnCNV (Detection and Annotation of Copy Number Variations from WES data), to meet the current demands of WES users. Upon submitting the file generated from WES data by an in-house tool that can be downloaded from our server, DeAnnCNV can detect CNVs in each sample and extract the shared CNVs among multiple samples. DeAnnCNV also provides additional useful supporting information for the detected CNVs and associated genes to help users to find the potential candidates for further experimental study. The web server is implemented in PHP + Perl + MATLAB and is online available to all users for free at http://mcg.ustc.edu.cn/db/cnv/.

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC4489280 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data.

Zhang Yuanwei Y   Yu Zhenhua Z   Ban Rongjun R   Zhang Huan H   Iqbal Furhan F   Zhao Aiwu A   Li Ao A   Shi Qinghua Q  

Nucleic acids research 20150526 W1

With the decrease in costs, whole-exome sequencing (WES) has become a very popular and powerful tool for the identification of genetic variants underlying human diseases. However, integrated tools to precisely detect and systematically annotate copy number variations (CNVs) from WES data are still in great demand. Here, we present an online tool, DeAnnCNV (Detection and Annotation of Copy Number Variations from WES data), to meet the current demands of WES users. Upon submitting the file generat  ...[more]

Similar Datasets

Unknown CEQer: a graphical tool for copy number and allelic imbalance detection from whole-exome sequencing data.
| S-EPMC3790773 | biostudies-literature
Unknown VEGAWES: variational segmentation on whole exome sequencing for copy number detection.
| S-EPMC4587906 | biostudies-literature
Unknown WISExome: a within-sample comparison approach to detect copy number variations in whole exome sequencing data.
| S-EPMC5865163 | biostudies-other
Unknown inCNV: An Integrated Analysis Tool for Copy Number Variation on Whole Exome Sequencing.
| S-EPMC7520931 | biostudies-literature
Unknown Enhanced copy number variants detection from whole-exome sequencing data using EXCAVATOR2.
| S-EPMC5175347 | biostudies-literature
Unknown Comparative study of whole exome sequencing-based copy number variation detection tools.
| S-EPMC7059689 | biostudies-literature
Unknown A Sparse Model Based Detection of Copy Number Variations From Exome Sequencing Data.
| S-EPMC4808620 | biostudies-literature
Unknown CopyDetective: Detection threshold-aware copy number variant calling in whole-exome sequencing data.
| S-EPMC7604644 | biostudies-literature
Unknown CODEX: a normalization and copy number variation detection method for whole exome sequencing.
| S-EPMC4381046 | biostudies-literature
Unknown EXCAVATOR: detecting copy number variants from whole-exome sequencing data.
| S-EPMC4053953 | biostudies-literature