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Combined optical and electronic sensing of epithelial cells using planar organic transistors.

ABSTRACT: A planar, conducting-polymer-based transistor for combined optical and electronic monitoring of live cells provides a unique platform for monitoring the health of cells in vitro. Monitoring of MDCK-I epithelial cells over several days is shown, along with a demonstration of the device for toxicology studies, of use in future drug discovery or diagnostics applications.

SUBMITTER: Ramuz M

PROVIDER: S-EPMC4489338 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature

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Combined optical and electronic sensing of epithelial cells using planar organic transistors.

Ramuz Marc M Hama Adel A Huerta Miriam M Rivnay Jonathan J Leleux Pierre P Owens Róisín M RM

Advanced materials (Deerfield Beach, Fla.) 20140901 41

A planar, conducting-polymer-based transistor for combined optical and electronic monitoring of live cells provides a unique platform for monitoring the health of cells in vitro. Monitoring of MDCK-I epithelial cells over several days is shown, along with a demonstration of the device for toxicology studies, of use in future drug discovery or diagnostics applications. ...[more]

PMID: 25179835

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