Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation.
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ABSTRACT:
SUBMITTER: Savall J
PROVIDER: S-EPMC4490062 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Publications
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation.
Savall Joan J Ho Eric Tatt Wei ETW Huang Cheng C Maxey Jessica R JR Schnitzer Mark J MJ
Nature methods 20150525 7
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex at ...[more]
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