Dataset Information

Complete Genomic Sequence of Issyk-Kul Virus.

ABSTRACT: Issyk-Kul virus (ISKV) is an ungrouped virus tentatively assigned to the Bunyaviridae family and is associated with an acute febrile illness in several central Asian countries. Using next-generation sequencing technologies, we report here the full-genome sequence for this novel unclassified arboviral pathogen circulating in central Asia.

SUBMITTER: Atkinson B

PROVIDER: S-EPMC4490839 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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Complete Genomic Sequence of Issyk-Kul Virus.

Atkinson Barry B Marston Denise A DA Ellis Richard J RJ Fooks Anthony R AR Hewson Roger R

Genome announcements 20150702 4

Issyk-Kul virus (ISKV) is an ungrouped virus tentatively assigned to the Bunyaviridae family and is associated with an acute febrile illness in several central Asian countries. Using next-generation sequencing technologies, we report here the full-genome sequence for this novel unclassified arboviral pathogen circulating in central Asia. ...[more]

PMID: 26139711

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Project description:The water resources of Central Asia play an important role in maintaining the fragile balance of ecosystems and the sustainable development of human society. However, the lack of research on the heavy metals in river waters has a far-reaching influence on public health and the sustainable development in Central Asia. In order to reveal the possible sources of the heavy metals and to assess the associated human health risks, thirty-eight water samples were collected from the rivers of the Issyk-Kul Basin during the period with low river flow (May) and the period with high river flow (July and August), and the hydrochemical compositions and major ions of heavy metals were analyzed. No changes in hydrochemical facies were observed between the two periods and the river water type was calcium bicarbonate. Carbonate dissolution and silicate weathering controlled the variation of cations and anions in river waters from the Issyk-Kul Basin. There were some differences in the sources of heavy metals in water bodies between the two periods. During the period with low river flow, heavy metals (Cr) were closely clustered with major ions, indicating that they were mainly affected by water-rock interactions. During the period with high river flow, all heavy metals studied in this paper had different sources of major ions, and the heavy metals maybe influenced by human activities. From the human health risk assessment, the hazard quotients for all samples were less than 1, reflecting that there was no noncarcinogenic risk in the river waters of the Issyk-Kul Basin during the two sampling periods. However, the water samples with carcinogenic risk of arsenic exceeding the threshold (10-4) accounted for 21.1% of the total, indicating that there were some certain carcinogenic hazards for human health via water drinking with direct oral ingestion. The results are of certain significance for the utilization and protection of water resources in the basin as well as the protection of public health.

Dataset Information

Complete Genomic Sequence of Issyk-Kul Virus.

Publications

Complete Genomic Sequence of Issyk-Kul Virus.

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