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The confusion assessment method for the intensive care unit in patients with cirrhosis.


ABSTRACT: In the intensive care unit (ICU), delirium is routinely measured with the widely-used, validated Confusion Assessment Method for the ICU (CAM-ICU), but CAM-ICU has not been studied in patients with cirrhosis. We studied a group of patients with cirrhosis to determine the relationship between delirium measured by CAM-ICU and clinical outcomes. Consecutive patients with cirrhosis admitted to the ICU from 2009 to 2012 were included in a retrospective cohort study. Patients were screened twice daily for coma and delirium during their ICU stay using the Richmond Agitation Sedation Scale (RASS) and CAM-ICU. The association between delirium/coma and mortality was determined using multiple logistic regression. RASS and CAM-ICU were also compared to a retrospective assessment of hepatic encephalopathy (HE). Of 91 patients with cirrhosis, 26 (28.6 %) developed delirium/coma. RASS/CAM-ICU had fair agreement with the HE assessment (? 0.38). Patients with delirium/coma had numerically greater mortality in-hospital (23.1 vs. 7.7 %, p?=?0.07) and at 90 days (30.8 vs. 18.5 %, p?=?0.26), and they also had longer hospital length of stay (median 19.5 vs. 6 days, p?

SUBMITTER: Orman ES 

PROVIDER: S-EPMC4492810 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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The confusion assessment method for the intensive care unit in patients with cirrhosis.

Orman Eric S ES   Perkins Anthony A   Ghabril Marwan M   Khan Babar A BA   Chalasani Naga N   Boustani Malaz A MA  

Metabolic brain disease 20150507 4


In the intensive care unit (ICU), delirium is routinely measured with the widely-used, validated Confusion Assessment Method for the ICU (CAM-ICU), but CAM-ICU has not been studied in patients with cirrhosis. We studied a group of patients with cirrhosis to determine the relationship between delirium measured by CAM-ICU and clinical outcomes. Consecutive patients with cirrhosis admitted to the ICU from 2009 to 2012 were included in a retrospective cohort study. Patients were screened twice daily  ...[more]

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