Current approaches in treatment of triple-negative breast cancer.
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ABSTRACT:
SUBMITTER: Wahba HA
PROVIDER: S-EPMC4493381 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Current approaches in treatment of triple-negative breast cancer.
Wahba Hanan Ahmed HA El-Hadaad Hend Ahmed HA
Cancer biology & medicine 20150601 2
Triple-negative breast cancer (TNBC) is diagnosed more frequently in younger and premenopausal women and is highly prevalent in African American women. TNBC is a term derived from tumors that are characterized by the absence of ER, PgR, and HER2. So patients with TNBC do not benefit from hormonal or trastuzumab-based therapies. TNBCs are biologically aggressive, although some reports suggest that they respond to chemotherapy better than other types of breast cancer, prognosis remains poor. This ...[more]
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