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Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures.

ABSTRACT: The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community data to probe these associations, a repository of structural and functional magnetic resonance imaging (MRI) scans linked to genetic information was constructed from a sample of healthy individuals. The initial release, detailed in the present manuscript, encompasses quality screened cross-sectional data from 1,570 participants ages 18 to 35 years who were scanned with MRI and completed demographic and health questionnaires. Personality and cognitive measures were obtained on a subset of participants. Each dataset contains a T1-weighted structural MRI scan and either one (n=1,570) or two (n=1,139) resting state functional MRI scans. Test-retest reliability datasets are included from 69 participants scanned within six months of their initial visit. For the majority of participants self-report behavioral and cognitive measures are included (n=926 and n=892 respectively). Analyses of data quality, structure, function, personality, and cognition are presented to demonstrate the dataset's utility.

SUBMITTER: Holmes AJ

PROVIDER: S-EPMC4493828 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures.

Holmes Avram J AJ Hollinshead Marisa O MO O'Keefe Timothy M TM Petrov Victor I VI Fariello Gabriele R GR Wald Lawrence L LL Fischl Bruce B Rosen Bruce R BR Mair Ross W RW Roffman Joshua L JL Smoller Jordan W JW Buckner Randy L RL

Scientific data 20150707

The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community data to probe these associations, a repository of structural and functional magnetic resonance imaging (MRI) scans linked to genetic information was constructed from a sample of healthy individuals. The initial release, detailed in the present manuscript, encompasses quality scree ...[more]

PMID: 26175908

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Dataset Information

Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures.

Publications

Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures.

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