EBV-Associated Cancer and Autoimmunity: Searching for Therapies.
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ABSTRACT:
SUBMITTER: Capone G
PROVIDER: S-EPMC4494242 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
EBV-Associated Cancer and Autoimmunity: Searching for Therapies.
Capone Giovanni G Fasano Candida C Lucchese Guglielmo G Calabrò Michele M Kanduc Darja D
Vaccines 20150205 1
Epstein-Barr virus (EBV) infects B-, T-, and NK cells and has been associated not only with a wide range of lymphoid malignancies but also with autoimmune diseases such as lupus erythematosus, rheumatoid arthritis and, in particular, multiple sclerosis. Hence, effective immunotherapeutic approaches to eradicate EBV infection might overthrow cancer and autoimmunity incidence. However, currently no effective anti-EBV immunotherapy is available. Here we use the concept that protein immunogenicity i ...[more]
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