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ITagPlot: an accurate computation and interactive drawing tool for tag density plot.


ABSTRACT: Tag density plots are very important to intuitively reveal biological phenomena from capture-based sequencing data by visualizing the normalized read depth in a region.We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summary statistics and unsupervised clustering.http://sourceforge.net/projects/itagplot/.

SUBMITTER: Kim SH 

PROVIDER: S-EPMC4495303 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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iTagPlot: an accurate computation and interactive drawing tool for tag density plot.

Kim Sung-Hwan SH   Ezenwoye Onyeka O   Cho Hwan-Gue HG   Robertson Keith D KD   Choi Jeong-Hyeon JH  

Bioinformatics (Oxford, England) 20150319 14


<h4>Motivation</h4>Tag density plots are very important to intuitively reveal biological phenomena from capture-based sequencing data by visualizing the normalized read depth in a region.<h4>Results</h4>We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summary sta  ...[more]

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