Ontology highlight
ABSTRACT:
SUBMITTER: Dayan G
PROVIDER: S-EPMC4497892 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Dayan Gustavo G Arredondo Jose L JL Carrasquilla Gabriel G Deseda Carmen C CC Dietze Reynaldo R Luz Kleber K Costa Maria Selma N MSN Cunha Rivaldo V RV Rey Luis C LC Morales Javier J Reynales Humberto H Miranda Maria M Zambrano Betzana B Rivas Enrique E Garbes Pedro P Noriega Fernando F
The American journal of tropical medicine and hygiene 20150526 1
To prepare for a Phase III dengue vaccine efficacy trial, 20 investigational sites were selected for this observational study to identify dengue infections in a closed cohort (N = 3,000 children 9-16 years of age). Of 255 acute febrile episodes experienced by 235 children, 50 (21.3%) were considered serologically probable dengue, and 18 (7.7%) were considered virologically confirmed (i.e., dengue NS1 antigen positive) dengue cases. Considering the disease-free and at-risk period from study start ...[more]