Ontology highlight
ABSTRACT:
SUBMITTER: Mettananda S
PROVIDER: S-EPMC4497969 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Mettananda Sachith S Gibbons Richard J RJ Higgs Douglas R DR
Blood 20150413 24
The thalassemias, together with sickle cell anemia and its variants, are the world's most common form of inherited anemia, and in economically undeveloped countries, they still account for tens of thousands of premature deaths every year. In developed countries, treatment of thalassemia is also still far from ideal, requiring lifelong transfusion or allogeneic bone marrow transplantation. Clinical and molecular genetic studies over the course of the last 50 years have demonstrated how coinherita ...[more]