Alterations in sucrose sham-feeding intake as a function of diet-exposure in rats maintained on calorically dense diets.

ABSTRACT: We previously reported that rats increase meal size upon initial presentation of a calorically dense diet. The increase may be attributed to increased orosensory stimulation and/or reduced sensitivity to post-ingestive inhibitory signals. During feeding both types of signals are simultaneously in play; thus here, we compare responses in rats presented a high-energy diet (HE) or 45% high-fat diet (HF) with those of chow-fed controls (CHOW) in a sham-feeding procedure in which post-ingestive feedback is minimized. Measures of sham-feeding to sucrose were taken before diet manipulation (baseline), ~5 days (dynamic phase) and ~6 weeks (static phase) following introduction of the palatable diet, as well as after animals were switched back to standard chow (recovery phase). Some but not all the

SUBMITTER: Treesukosol Y 

PROVIDER: S-EPMC4499488 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature