Ontology highlight
ABSTRACT:
SUBMITTER: Cui G
PROVIDER: S-EPMC4499796 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Cui Guangying G Xu Xuejun X Diao Hongyan H
Scientific reports 20150713
Tenofovir disoproxil fumarate (TDF) monotherapy has proven superior antiviral efficacy in chronic hepatitis B (CHB) patients; however, whether the combination of TDF and emtricitabine (FTC) exerts a significant advantage remains controversial. A meta-analysis was performed to comprehensively compare the therapeutic effects of FTC/TDF combination with TDF alone in CHB patients. Five studies involving 614 patients were identified, and subgroup analysis was performed based on the nucleos(t)ide trea ...[more]