A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia.
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ABSTRACT:
SUBMITTER: Huey ED
PROVIDER: S-EPMC4499854 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Publications
A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia.
Huey Edward D ED Putnam Karen T KT Grafman Jordan J
Neurology 20060101 1
<h4>Objective</h4>To evaluate neurotransmitter deficiencies and neurotransmitter-based treatments for frontotemporal dementia (FTD).<h4>Methods</h4>The authors conducted a systematic review of the literature on the mechanism and treatment of FTD and a meta-analysis of treatment studies of antidepressants for the behavioral symptoms of FTD.<h4>Results</h4>Patients with FTD show deficiencies in the serotonin and dopamine neurotransmitter systems, while the acetylcholine system appears relatively i ...[more]
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