Ontology highlight
ABSTRACT:
SUBMITTER: Migliore M
PROVIDER: S-EPMC4500266 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Migliore Michele M Cavarretta Francesco F Marasco Addolorata A Tulumello Eleonora E Hines Michael L ML Shepherd Gordon M GM
Proceedings of the National Academy of Sciences of the United States of America 20150622 27
How the olfactory bulb organizes and processes odor inputs through fundamental operations of its microcircuits is largely unknown. To gain new insight we focus on odor-activated synaptic clusters related to individual glomeruli, which we call glomerular units. Using a 3D model of mitral and granule cell interactions supported by experimental findings, combined with a matrix-based representation of glomerular operations, we identify the mechanisms for forming one or more glomerular units in respo ...[more]