Genetic Architecture of Transcription and Chromatin Regulation.
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ABSTRACT:
SUBMITTER: Kim K
PROVIDER: S-EPMC4500797 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Genetic Architecture of Transcription and Chromatin Regulation.
Kim Kwoneel K Bang Hyoeun H Lee Kibaick K Choi Jung Kyoon JK
Genomics & informatics 20150630 2
DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures. In particular, chromatin opening is tightly coupled with gene transcription. To understand how these two processes are genetically regulated and associated with each other, we examined the changes of chromatin accessibility and gene expression in response to genetic va ...[more]
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