Ontology highlight
ABSTRACT:
SUBMITTER: Martischnig AM
PROVIDER: S-EPMC4502273 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Martischnig Amadea M AM Mehilli Julinda J Pollak Janina J Petzold Tobias T Fiedler Anette K AK Mayer Katharina K Schulz-Schüpke Stefanie S Sibbing Dirk D Massberg Steffen S Kastrati Adnan A Sarafoff Nikolaus N
BioMed research international 20150701
<h4>Background</h4>A relevant number of patients receive triple therapy with clopidogrel, aspirin, and oral anticoagulation. Clopidogrel's efficacy on ADP induced platelet function may be influenced by concomitant antithrombotic therapies. Data regarding the effect of dabigatran on platelet function is limited to in vitro studies and healthy individuals.<h4>Methods</h4>The "Dabi-ADP-1" and "Dabi-ADP-2" trials randomized patients with atrial fibrillation to either dabigatran or phenprocoumon for ...[more]