Ontology highlight
ABSTRACT:
SUBMITTER: Farahani MS
PROVIDER: S-EPMC4502798 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Farahani Maryam Shahrabi MS Shahbazi Shirin S Moghaddam Soheila Amini SA Mahdian Reza R
Reproductive sciences (Thousand Oaks, Calif.) 20141030 6
Since the activation of KRAS results in de novo endometriosis in mice, KRAS is regarded as a crucial gene in ectopic endometrial implantation. Recently, it has been reported that 31% of women with endometriosis have KRAS let-7 complementary binding site 6 single-nucleotide polymorphism (LCS6 SNP). This study addresses the correlation between KRAS LCS6 SNP and endometriosis in a case-control study. To detect probable somatic mutation in ectopic endometrial tissue, we evaluated LCS6 SNP in cell-fr ...[more]