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Unusual skin manifestation of hand, foot and mouth disease associated with coxsackievirus A6: cases report.


ABSTRACT: BACKGROUND:Hand, food, and mouth disease (HFMD) is a highly contagious disease caused by enteroviruses infection. It is a health problem in young children under 5 years of age worldwide. The common causative agents are coxsackievirus A 16 (CA16) and enterovirus 71 (EV71). In recent years, coxsackievirus A6 (CA6) has emerged to be one of the major etiologic agents of HFMD worldwide including in Thailand. CASE DESCRIPTION:We reported cases with unusual skin manifestations of CA6-associated HFMD such as widespread severe cutaneous eruption, large vesicles (varicelliform), purpuric-like lesions or Gianotti-Crosti like eruptions. DISCUSSION AND EVALUATION:Molecular characterization of the CA6 strains from those patients found that all were clustered in the same group of CA6 that are currently circulating in Thailand. CONCLUSIONS:Clinicians need to be aware of the expanded range of cutaneous findings in CA6-associated HFMD in order to properly consider the diagnosis, management and prevention.

SUBMITTER: Chatproedprai S 

PROVIDER: S-EPMC4504872 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Unusual skin manifestation of hand, foot and mouth disease associated with coxsackievirus A6: cases report.

Chatproedprai Susheera S   Tempark Therdpong T   Wanlapakorn Nasamon N   Puenpa Jiratchaya J   Wananukul Siriwan S   Poovorawan Yong Y  

SpringerPlus 20150717


<h4>Background</h4>Hand, food, and mouth disease (HFMD) is a highly contagious disease caused by enteroviruses infection. It is a health problem in young children under 5 years of age worldwide. The common causative agents are coxsackievirus A 16 (CA16) and enterovirus 71 (EV71). In recent years, coxsackievirus A6 (CA6) has emerged to be one of the major etiologic agents of HFMD worldwide including in Thailand.<h4>Case description</h4>We reported cases with unusual skin manifestations of CA6-ass  ...[more]

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