Ontology highlight
ABSTRACT:
SUBMITTER: Sears PR
PROVIDER: S-EPMC4504973 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Sears Patrick R PR Yin Wei-Ning WN Ostrowski Lawrence E LE
American journal of physiology. Lung cellular and molecular physiology 20150515 2
Mucociliary clearance (MCC) is an important innate defense mechanism that continuously removes inhaled pathogens and particulates from the airways. Normal MCC is essential for maintaining a healthy respiratory system, and impaired MCC is a feature of many airway diseases, including both genetic (cystic fibrosis, primary ciliary dyskinesia) and acquired (chronic obstructive pulmonary disease, bronchiectasis) disorders. Research into the fundamental processes controlling MCC, therefore, has direct ...[more]