Ontology highlight
ABSTRACT:
SUBMITTER: Sato K
PROVIDER: S-EPMC4508660 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Sato Kazuhide K Nagaya Tadanobu T Mitsunaga Makoto M Choyke Peter L PL Kobayashi Hisataka H
Cancer letters 20150527 1
Lung metastases are a leading cause of cancer related deaths; nonetheless current treatments are limited. Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the specificity of intravenously injected antibodies that target tumors with the toxicity induced by photosensitizers activated by NIR-light. Herein, we demonstrate the efficacy of NIR-PIT in a mouse model of lung metastases. Experiments were conducted with a HER2, luciferase and GFP expressing cell line (3T3/ ...[more]