Ontology highlight
ABSTRACT:
SUBMITTER: Rosario FJ
PROVIDER: S-EPMC4509489 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Obesity (Silver Spring, Md.) 20150801 8
<h4>Objective</h4>To identify possible mechanisms linking obesity in pregnancy to increased fetal adiposity and growth, a unique mouse model of maternal obesity associated with fetal overgrowth was developed, and the hypothesis that maternal obesity causes up-regulation of placental nutrient transporter expression and activity was tested.<h4>Methods</h4>C57BL/6J female mice were fed a control (C) or a high-fat/high-sugar (HF/HS) pelleted diet supplemented by ad libitum access to sucrose (20%) so ...[more]