Ontology highlight
ABSTRACT:
SUBMITTER: Beims H
PROVIDER: S-EPMC4510184 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Beims Hannes H Wittmann Johannes J Bunk Boyke B Spröer Cathrin C Rohde Christine C Günther Gabi G Rohde Manfred M von der Ohe Werner W Steinert Michael M
Applied and environmental microbiology 20150605 16
Paenibacillus larvae is the causative agent of American foulbrood (AFB), the most serious honey bee brood bacterial disease. We isolated and characterized P. larvae-directed bacteriophages and developed criteria for safe phage therapy. Whole-genome analysis of a highly lytic virus of the family Siphoviridae (HB10c2) provided a detailed safety profile and uncovered its lysogenic nature and a putative beta-lactamase-like protein. To rate its antagonistic activity against the pathogens targeted and ...[more]