Ontology highlight
ABSTRACT:
SUBMITTER: Wade KH
PROVIDER: S-EPMC4510525 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20150722
Given that observational associations may be inaccurate, we used offspring blood pressure (BP) to provide alternative estimates of the associations between own BP and mortality. Observational associations between BP and mortality, estimated as hazard ratios (HRs) from Cox regression, were compared to HRs obtained using offspring BP as an instrumental variable (IV) for own BP (N = 32,227 mother-offspring and 27,535 father-offspring pairs). Observationally, there were positive associations between ...[more]