Nanopore back titration analysis of dipicolinic acid.
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ABSTRACT:
SUBMITTER: Han Y
PROVIDER: S-EPMC4511083 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
Nanopore back titration analysis of dipicolinic acid.
Han Yujing Y Zhou Shuo S Wang Liang L Guan Xiyun X
Electrophoresis 20141003 3
Here, we report a novel label-free nanopore back titration method for the detection of dipicolinic acid, a marker molecule for bacterial spores. By competitive binding of the target analyte and a large ligand probe to metal ions, dipicolinic acid could be sensitively and selectively detected. This nanopore back titration approach should find useful applications in the detection of other species of medical, biological, or environmental importance if their direct detection is difficult to achieve. ...[more]
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