Ontology highlight
ABSTRACT:
SUBMITTER: Rosler KS
PROVIDER: S-EPMC4513122 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Rosler Kirsten S KS Mercier Evan E Andrews Ian C IC Wieden Hans-Joachim HJ
The Journal of biological chemistry 20150527 30
GTPases perform a wide range of functions, ranging from protein synthesis to cell signaling. Of all known GTPases, only eight are conserved across all three domains of life. YchF is one of these eight universally conserved GTPases; however, its cellular function and enzymatic properties are poorly understood. YchF differs from the classical GTPases in that it has a higher affinity for ATP than for GTP and is a functional ATPase. As a hydrophobic amino acid-substituted ATPase, YchF does not posse ...[more]