Ontology highlight
ABSTRACT:
SUBMITTER: Khan MN
PROVIDER: S-EPMC4514076 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Khan M Nadeem MN Pichichero Michael E ME
Human vaccines & immunotherapeutics 20140101 12
The human nasopharynx (NP) microbiota is complex and diverse and Streptococcus pneumoniae (pneumococcus) is a frequent member. In the first few years of life, children experience maturation of their immune system thereby conferring homeostatic balance in which pneumococci are typically rendered as harmless colonizers in the upper respiratory environment. Pneumococcal carriage declines in many children before they acquire capsular-specific antibodies, suggesting a capsule antibody-independent mec ...[more]