Ontology highlight
ABSTRACT:
SUBMITTER: Fattom A
PROVIDER: S-EPMC4514248 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Human vaccines & immunotherapeutics 20150101 3
In a previous study in end-stage renal disease (ESRD) hemodialysis patients, a single dose of Staphylococcus aureus type 5 and 8 capsular polysaccharides (T5/T8) conjugated to nontoxic recombinant Pseudomonas aeruginosa exotoxin A investigational vaccine showed no efficacy against S. aureus bacteremia 1 year post-vaccination, but a trend for efficacy was observed over the first 40 weeks post-vaccination. Vaccine efficacy (VE) of 2 vaccine doses was therefore evaluated. In a double-blind trial 33 ...[more]