Ontology highlight
ABSTRACT:
SUBMITTER: Bedke J
PROVIDER: S-EPMC4514323 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bedke Jens J Kruck Stephan S Gakis Georgios G Stenzl Arnulf A Goebell Peter J PJ
Human vaccines & immunotherapeutics 20150101 5
The introduction of targeted therapies like the tyrosine kinase (TKI) and mammalian target of rapamycin (mTOR) inhibitors has improved patients' survival in general. Nevertheless the prognosis remains limited. Therapies with a new mode of action are urgently warranted, especially those who would provoke long-term responders or long-lasting complete remissions as observed with unspecific immunotherapy with the cytokines interleukin-2 and interferon-α. In the recent years a deeper understanding of ...[more]