Ontology highlight
ABSTRACT:
SUBMITTER: Grieb M
PROVIDER: S-EPMC4514755 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Grieb Melanie M Burkovski Andre A Sträng J Eric JE Kraus Johann M JM Groß Alexander A Palm Günther G Kühl Michael M Kestler Hans A HA
PloS one 20150724 7
Gene interactions in cells can be represented by gene regulatory networks. A Boolean network models gene interactions according to rules where gene expression is represented by binary values (on / off or {1, 0}). In reality, however, the gene's state can have multiple values due to biological properties. Furthermore, the noisy nature of the experimental design results in uncertainty about a state of the gene. Here we present a new Boolean network paradigm to allow intermediate values on the inte ...[more]