Ontology highlight
ABSTRACT:
SUBMITTER: Hill-Cousins JT
PROVIDER: S-EPMC4516318 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Organic letters 20150421 9
The synthesis of an octa-alkoxy substituted isotopically labeled naphthalene derivative, shown to have excellent properties in singlet NMR experiments, is described. This highly substituted naphthalene system, which incorporates an adjacent (13)C spin pair, is readily accessed from a commercially available (13)C2-labeled building block via sequential thermal alkynyl- and arylcyclobutenone rearrangements. The synthetic route incorporates a simple desymmetrization approach leading to a small diffe ...[more]