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First-in-Class CDK4/6 Inhibitor Palbociclib Could Usher in a New Wave of Combination Therapies for HR+, HER2- Breast Cancer.


ABSTRACT: Women with hormone receptor-positive, human epidermal growth factor receptor 2- negative breast cancer-the most common subtype-have new options as palbociclib and similar drugs debut. This article outlines the rationale and evidence for their use.

SUBMITTER: McCain J 

PROVIDER: S-EPMC4517534 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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First-in-Class CDK4/6 Inhibitor Palbociclib Could Usher in a New Wave of Combination Therapies for HR+, HER2- Breast Cancer.

McCain Jack J  

P & T : a peer-reviewed journal for formulary management 20150801 8


Women with hormone receptor-positive, human epidermal growth factor receptor 2- negative breast cancer-the most common subtype-have new options as palbociclib and similar drugs debut. This article outlines the rationale and evidence for their use. ...[more]

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