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A new gyrovirus in human feces.

ABSTRACT: A novel gyrovirus genome found in the feces of an adult with diarrhea is described. The genome shows the three expected main ORFs encoding a structural protein (VP1), nonstructural protein (VP2), and Apoptin protein (VP3), which shared identities of 41, 42, and 38 % with those of the most closely related gyrovirus proteins, respectively. Given the high divergence in its genome, this gyrovirus may be considered the prototype for a new viral species (GyV9) in the Gyrovirus genus. Because the closest relatives of this gyrovirus infect chicken, a possible dietary origin for the presence of this virus in human feces is discussed.

SUBMITTER: Phan TG

PROVIDER: S-EPMC4519424 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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A new gyrovirus in human feces.

Phan Tung Gia TG da Costa Antonio Charlys AC Zhang Wen W Pothier Pierre P Ambert-Balay Katia K Deng Xutao X Delwart Eric E

Virus genes 20150527 1

A novel gyrovirus genome found in the feces of an adult with diarrhea is described. The genome shows the three expected main ORFs encoding a structural protein (VP1), nonstructural protein (VP2), and Apoptin protein (VP3), which shared identities of 41, 42, and 38 % with those of the most closely related gyrovirus proteins, respectively. Given the high divergence in its genome, this gyrovirus may be considered the prototype for a new viral species (GyV9) in the Gyrovirus genus. Because the close ...[more]

PMID: 26013257

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