Elastic properties of organ of Corti tissues from point-stiffness measurement and inverse analysis.
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ABSTRACT:
SUBMITTER: Zagadou BF
PROVIDER: S-EPMC4519624 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
Elastic properties of organ of Corti tissues from point-stiffness measurement and inverse analysis.
Zagadou B F BF Barbone P E PE Mountain D C DC
Journal of biomechanics 20140220 6
We describe a method to use point-stiffness (PtSt) measurements, i.e., indentation measurements, to obtain elastic moduli of different organ of Corti (OC) tissues. A detailed finite element (FE) model of the OC is used to account for geometric effects in the indentation measurements. We also present a sensitivity analysis, performed within a Bayesian estimation framework, that can be used to improve experimental design. The sensitivity analysis shows that the basilar membrane (BM) PtSt is most s ...[more]
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