Time to progression of pancreatic ductal adenocarcinoma from low-to-high tumour stages.

ABSTRACT:

Objective

Although pancreatic ductal adenocarcinoma is considered a rapidly progressive disease, mathematical models estimate that it takes many years for an initiating pancreatic cancer cell to grow into an advanced stage cancer. In order to estimate the time it takes for a pancreatic cancer to progress through different tumor, node, metastasis (TNM) stages, we compared the mean age of patients with pancreatic cancers of different sizes and stages.

Design

Patient age, tumour size, stage and demographic information were analysed for 13,131 patients with pancreatic ductal adenocarcinoma entered into the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) database. Multiple linear regression models for age were generated, adjusting for patient ethnici

SUBMITTER: Yu J 

PROVIDER: S-EPMC4520782 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature