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Vaccines for Pseudomonas aeruginosa: a long and winding road.


ABSTRACT: Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no vaccine against this bacteria has come to market. This review describes the current state-of-the-art in vaccinology for this bacterium. This includes a discussion of those at risk for infection, the types of vaccines and the approaches for empirical and targeted antigen selection under development, as well as a perspective on where the field should go. In addition, the challenges in developing a vaccine for those individuals at risk are discussed.

SUBMITTER: Priebe GP 

PROVIDER: S-EPMC4521563 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Vaccines for Pseudomonas aeruginosa: a long and winding road.

Priebe Gregory P GP   Goldberg Joanna B JB  

Expert review of vaccines 20140227 4


Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no vaccine against this bacteria has come to market. This review describes the current state-of-the-art in vaccinology for this bacterium. This includes a discussion of those at risk for infection, the types of vaccines and the approaches for empirical and targeted antigen selection under development, as well as a perspective on where the field should go. In addition, the challenges in developing a vaccine for those  ...[more]

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