Ontology highlight
ABSTRACT:
SUBMITTER: Jayakumar A
PROVIDER: S-EPMC4521594 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Jayakumar A A Vittinghoff E E Segal M R MR MacKenzie W R WR Johnson J L JL Gitta P P Saukkonen J J Anderson J J Weiner M M Engle M M Yoon C C Kato-Maeda M M Nahid P P
Tuberculosis (Edinburgh, Scotland) 20150509 4
<h4>Rationale</h4>Biomarkers for monitoring response to anti-tuberculosis treatment are needed. We explored immune markers previously published as having predictive capability for 8 week culture status in 39 adults enrolled in a clinical trial in Kampala, Uganda.<h4>Methods</h4>We consecutively selected 20 HIV-negative pulmonary TB subjects with positive cultures, and 19 subjects with negative cultures at the end of intensive phase therapy. At baseline and after 8 weeks, serum was assayed for ni ...[more]