Ontology highlight
ABSTRACT:
SUBMITTER: Benedictus L
PROVIDER: S-EPMC4522679 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Benedictus Lindert L Luteijn Rutger D RD Otten Henny H Lebbink Robert Jan RJ van Kooten Peter J S PJ Wiertz Emmanuel J H J EJ Rutten Victor P M G VP Koets Ad P AP
Scientific reports 20150803
Bovine Neonatal Pancytopenia (BNP), a fatal bleeding syndrome of neonatal calves, is caused by maternal alloantibodies absorbed from colostrum and is characterized by lymphocytopenia, thrombocytopenia and bone marrow hypoplasia. An inactivated viral vaccine is the likely source of alloantigens inducing BNP-associated alloantibodies in the dam. In this study the specificity of BNP alloantibodies was assessed and was linked to the pathology of BNP. We demonstrated that Major Histocompatibility Com ...[more]