Ontology highlight
ABSTRACT:
SUBMITTER: Badrinarayanan A
PROVIDER: S-EPMC4523614 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Badrinarayanan Anjana A Le Tung B K TB Laub Michael T MT
The Journal of cell biology 20150801 3
Double-strand breaks (DSBs) can lead to the loss of genetic information and cell death. Although DSB repair via homologous recombination has been well characterized, the spatial organization of this process inside cells remains poorly understood, and the mechanisms used for chromosome resegregation after repair are unclear. In this paper, we introduced site-specific DSBs in Caulobacter crescentus and then used time-lapse microscopy to visualize the ensuing chromosome dynamics. Damaged loci rapid ...[more]