Ontology highlight
ABSTRACT:
SUBMITTER: Bounafaa A
PROVIDER: S-EPMC4524730 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bounafaa Abdelghani A Berrougui Hicham H Ghalim Noreddine N Nasser Boubker B Bagri Abdallah A Moujahid Abderrahmane A Ikhlef Souad S Camponova Pamela P Yamoul Najoua N Simo Olivier Kamtchueng OK Essamadi Abdelkhalid A Khalil Abdelouahed A
PloS one 20150804 8
The purpose of the present study was to investigate the distribution of PON1 Q192R and L55M polymorphisms and activities in a North African population and to determine their association with cardiovascular complications. The prevalence of the QQ, QR, RR, LL, LM, and MM genotypes in the study population was 55.4%, 34.09%, 9.83%, 41.97%, 48.20%, and 9.83% respectively. The Q, R, L, and M alleles had a gene frequency of 0.755, 0.245, 0.67, and 0.33, respectively. The PON1 192 RR genotype was signif ...[more]