Cerebrospinal Fluid Biomarkers in Spinocerebellar Ataxia: A Pilot Study.
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ABSTRACT:
SUBMITTER: Brouillette AM
PROVIDER: S-EPMC4525756 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Cerebrospinal Fluid Biomarkers in Spinocerebellar Ataxia: A Pilot Study.
Brouillette Ashley M AM Öz Gülin G Gomez Christopher M CM
Disease markers 20150722
Neurodegenerative diseases, including the spinocerebellar ataxias (SCA), would benefit from the identification of reliable biomarkers that could serve as disease subtype-specific and stage-specific indicators for the development and monitoring of treatments. We analyzed the cerebrospinal fluid (CSF) level of tau, α-synuclein, DJ-1, and glial fibrillary acidic protein (GFAP), proteins previously associated with neurodegenerative processes, in patients with the autosomal dominant SCA1, SCA2, and S ...[more]
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