Ontology highlight
ABSTRACT:
SUBMITTER: Wang ZH
PROVIDER: S-EPMC4526054 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Wang Zhao-Hui ZH Zhao Zhi-Jun ZJ Xu Kang K Sun Guo-Bing GB Song Lin L Yin Hong-Xiang HX Chen Xiao-Qi XQ
Molecular medicine reports 20150518 3
Hereditary protein S (PS) deficiency is an independent risk factor for venous thromboembolism. However, the correlation between PS and arterial thrombotic disease, such as cerebral thrombosis, is not clear. The present study focused on the molecular mechanisms underlying ischemic stroke caused by a PS gene mutation in one family. The activity of antithrombin, protein C and PS in the plasma of the proband was measured, and the genes encoding PS were amplified and sequenced. The cellular localizat ...[more]