Modeling for (physical) biologists: an introduction to the rule-based approach.
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ABSTRACT:
SUBMITTER: Chylek LA
PROVIDER: S-EPMC4526164 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Publications
Modeling for (physical) biologists: an introduction to the rule-based approach.
Chylek Lily A LA Harris Leonard A LA Faeder James R JR Hlavacek William S WS
Physical biology 20150716 4
Models that capture the chemical kinetics of cellular regulatory networks can be specified in terms of rules for biomolecular interactions. A rule defines a generalized reaction, meaning a reaction that permits multiple reactants, each capable of participating in a characteristic transformation and each possessing certain, specified properties, which may be local, such as the state of a particular site or domain of a protein. In other words, a rule defines a transformation and the properties tha ...[more]
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