Streptococcus mutans copes with heat stress by multiple transcriptional regulons modulating virulence and energy metabolism.
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ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC4528225 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
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Streptococcus mutans copes with heat stress by multiple transcriptional regulons modulating virulence and energy metabolism.
Liu Chengcheng C Niu Yulong Y Zhou Xuedong X Zheng Xin X Wang Shida S Guo Qiang Q Li Yuqing Y Li Mingyun M Li Jiyao J Yang Yi Y Ding Yi Y Lamont Richard J RJ Xu Xin X
Scientific reports 20150807
Dental caries is closely associated with the virulence of Streptococcus mutans. The virulence expression of S. mutans is linked to its stress adaptation to the changes in the oral environment. In this work we used whole-genome microarrays to profile the dynamic transcriptomic responses of S. mutans during physiological heat stress. In addition, we evaluated the phenotypic changes, including, eDNA release, initial biofilm formation, extracellular polysaccharides generation, acid production/acid t ...[more]
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2007-09-01 | GSE8922 | GEO