Ontology highlight
ABSTRACT:
SUBMITTER: Mitra AK
PROVIDER: S-EPMC4528621 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Mitra Anirban K AK Davis David A DA Tomar Sunil S Roy Lynn L Gurler Hilal H Xie Jia J Lantvit Daniel D DD Cardenas Horacio H Fang Fang F Liu Yueying Y Loughran Elizabeth E Yang Jing J Sharon Stack M M Emerson Robert E RE Cowden Dahl Karen D KD V Barbolina Maria M Nephew Kenneth P KP Matei Daniela D Burdette Joanna E JE
Gynecologic oncology 20150605 2
<h4>Objective</h4>Genomic studies of ovarian cancer (OC) cell lines frequently used in research revealed that these cells do not fully represent high-grade serous ovarian cancer (HGSOC), the most common OC histologic type. However, OC lines that appear to genomically resemble HGSOC have not been extensively used and their growth characteristics in murine xenografts are essentially unknown.<h4>Methods</h4>To better understand growth patterns and characteristics of HGSOC cell lines in vivo, CAOV3, ...[more]