Ontology highlight
ABSTRACT:
SUBMITTER: Charron S
PROVIDER: S-EPMC4529093 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Charron Sabine S Roubertie François F Benoist David D Dubes Virginie V Gilbert Stephen H SH Constantin Marion M Vieillot Delphine D Elbes Delphine D Quesson Bruno B Bordachar Pierre P Haissaguerre Michel M Bernus Olivier O Thambo Jean-Benoit JB Rooryck Caroline C
PloS one 20150807 8
Surgical repair of Tetralogy of Fallot (TOF) is highly successful but may be complicated in adulthood by arrhythmias, sudden death, and right ventricular or biventricular dysfunction. To better understand the molecular and cellular mechanisms of these delayed cardiac events, a chronic animal model of postoperative TOF was studied using microarrays to perform cardiac transcriptomic studies. The experimental study included 12 piglets (7 rTOF and 5 controls) that underwent surgery at age 2 months a ...[more]