Ontology highlight
ABSTRACT:
SUBMITTER: Kail M
PROVIDER: S-EPMC452929 | biostudies-literature | 1991 Sep
REPOSITORIES: biostudies-literature
Kail M M Hollinshead M M Ansorge W W Pepperkok R R Frank R R Griffiths G G Vaux D D
The EMBO journal 19910901 9
Intracellular alphavirus nucleocapsids express a binding site for the cytoplasmic domain of the viral E2 spike glycoprotein. This binding site is recognized by the anti-idiotype monoclonal antibody, F13. The monoclonal anti-anti-idiotype antibody, raised against F13 and designated 3G10, recognizes the carboxy-terminal eight residues of the E2 cytoplasmic domain in Semliki Forest virus (SFV), identifying this as the signal for nucleocapsid interaction. F13 binding to cells infected with SFV or a ...[more]