Cell Invasion in Collagen Scaffold Architectures Characterized by Percolation Theory.
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ABSTRACT:
SUBMITTER: Ashworth JC
PROVIDER: S-EPMC4529738 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Cell Invasion in Collagen Scaffold Architectures Characterized by Percolation Theory.
Ashworth Jennifer C JC Mehr Marco M Buxton Paul G PG Best Serena M SM Cameron Ruth E RE
Advanced healthcare materials 20150416 9
The relationship between biological scaffold interconnectivity and cell migration is an important but poorly understood factor in tissue regeneration. Here a scale-independent technique for characterization of collagen scaffold interconnectivity is presented, using a combination of X-ray microcomputed tomography and percolation theory. Confocal microscopy of connective tissue cells reveals this technique as highly relevant for determining the extent of cell invasion. ...[more]
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