Cell Invasion in Collagen Scaffold Architectures Characterized by Percolation Theory.

ABSTRACT: The relationship between biological scaffold interconnectivity and cell migration is an important but poorly understood factor in tissue regeneration. Here a scale-independent technique for characterization of collagen scaffold interconnectivity is presented, using a combination of X-ray microcomputed tomography and percolation theory. Confocal microscopy of connective tissue cells reveals this technique as highly relevant for determining the extent of cell invasion.

SUBMITTER: Ashworth JC 

PROVIDER: S-EPMC4529738 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature