A promoter-level mammalian expression atlas.
Ontology highlight
ABSTRACT:
SUBMITTER: FANTOM Consortium and the RIKEN PMI and CLST (DGT)
PROVIDER: S-EPMC4529748 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Publications
A promoter-level mammalian expression atlas.
Forrest Alistair R R AR Kawaji Hideya H Rehli Michael M Baillie J Kenneth JK de Hoon Michiel J L MJ Haberle Vanja V Lassmann Timo T Kulakovskiy Ivan V IV Lizio Marina M Itoh Masayoshi M Andersson Robin R Mungall Christopher J CJ Meehan Terrence F TF Schmeier Sebastian S Bertin Nicolas N Jørgensen Mette M Dimont Emmanuel E Arner Erik E Schmidl Christian C Schaefer Ulf U Medvedeva Yulia A YA Plessy Charles C Vitezic Morana M Severin Jessica J Semple Colin A C Ishizu Yuri Y Young Robert S RS Francescatto Margherita M Alam Intikhab I Albanese Davide D Altschuler Gabriel M GM Arakawa Takahiro T Archer John A C JA Arner Peter P Babina Magda M Rennie Sarah S Balwierz Piotr J PJ Beckhouse Anthony G AG Pradhan-Bhatt Swati S Blake Judith A JA Blumenthal Antje A Bodega Beatrice B Bonetti Alessandro A Briggs James J Brombacher Frank F Burroughs A Maxwell AM Califano Andrea A Cannistraci Carlo V CV Carbajo Daniel D Chen Yun Y Chierici Marco M Ciani Yari Y Clevers Hans C HC Dalla Emiliano E Davis Carrie A CA Detmar Michael M Diehl Alexander D AD Dohi Taeko T Drabløs Finn F Edge Albert S B AS Edinger Matthias M Ekwall Karl K Endoh Mitsuhiro M Enomoto Hideki H Fagiolini Michela M Fairbairn Lynsey L Fang Hai H Farach-Carson Mary C MC Faulkner Geoffrey J GJ Favorov Alexander V AV Fisher Malcolm E ME Frith Martin C MC Fujita Rie R Fukuda Shiro S Furlanello Cesare C Furino Masaaki M Furusawa Jun-ichi J Geijtenbeek Teunis B TB Gibson Andrew P AP Gingeras Thomas T Goldowitz Daniel D Gough Julian J Guhl Sven S Guler Reto R Gustincich Stefano S Ha Thomas J TJ Hamaguchi Masahide M Hara Mitsuko M Harbers Matthias M Harshbarger Jayson J Hasegawa Akira A Hasegawa Yuki Y Hashimoto Takehiro T Herlyn Meenhard M Hitchens Kelly J KJ Ho Sui Shannan J SJ Hofmann Oliver M OM Hoof Ilka I Hori Furni F Huminiecki Lukasz L Iida Kei K Ikawa Tomokatsu T Jankovic Boris R BR Jia Hui H Joshi Anagha A Jurman Giuseppe G Kaczkowski Bogumil B Kai Chieko C Kaida Kaoru K Kaiho Ai A Kajiyama Kazuhiro K Kanamori-Katayama Mutsumi M Kasianov Artem S AS Kasukawa Takeya T Katayama Shintaro S Kato Sachi S Kawaguchi Shuji S Kawamoto Hiroshi H Kawamura Yuki I YI Kawashima Tsugumi T Kempfle Judith S JS Kenna Tony J TJ Kere Juha J Khachigian Levon M LM Kitamura Toshio T Klinken S Peter SP Knox Alan J AJ Kojima Miki M Kojima Soichi S Kondo Naoto N Koseki Haruhiko H Koyasu Shigeo S Krampitz Sarah S Kubosaki Atsutaka A Kwon Andrew T AT Laros Jeroen F J JF Lee Weonju W Lennartsson Andreas A Li Kang K Lilje Berit B Lipovich Leonard L Mackay-Sim Alan A Manabe Ri-ichiroh R Mar Jessica C JC Marchand Benoit B Mathelier Anthony A Mejhert Niklas N Meynert Alison A Mizuno Yosuke Y de Lima Morais David A DA Morikawa Hiromasa H Morimoto Mitsuru M Moro Kazuyo K Motakis Efthymios E Motohashi Hozumi H Mummery Christine L CL Murata Mitsuyoshi M Nagao-Sato Sayaka S Nakachi Yutaka Y Nakahara Fumio F Nakamura Toshiyuki T Nakamura Yukio Y Nakazato Kenichi K van Nimwegen Erik E Ninomiya Noriko N Nishiyori Hiromi H Noma Shohei S Noma Shohei S Noazaki Tadasuke T Ogishima Soichi S Ohkura Naganari N Ohimiya Hiroko H Ohno Hiroshi H Ohshima Mitsuhiro M Okada-Hatakeyama Mariko M Okazaki Yasushi Y Orlando Valerio V Ovchinnikov Dmitry A DA Pain Arnab A Passier Robert R Patrikakis Margaret M Persson Helena H Piazza Silvano S Prendergast James G D JG Rackham Owen J L OJ Ramilowski Jordan A JA Rashid Mamoon M Rashid Mamoon M Ravasi Timothy T Rizzu Patrizia P Roncador Marco M Roy Sugata S Rye Morten B MB Saijyo Eri E Sajantila Antti A Saka Akiko A Sakaguchi Shimon S Sakai Mizuho M Sato Hiroki H Savvi Suzana S Saxena Alka A Schneider Claudio C Schultes Erik A EA Schulze-Tanzil Gundula G GG Schwegmann Anita A Sengstag Thierry T Sheng Guojun G Shimoji Hisashi H Shimoni Yishai Y Shin Jay W JW Simon Christophe C Sugiyama Daisuke D Sugiyama Takaai T Suzuki Masanori M Suzuki Naoko N Swoboda Rolf K RK 't Hoen Peter A C PA Tagami Michihira M Takahashi Naoko N Takai Jun J Tanaka Hiroshi H Tatsukawa Hideki H Tatum Zuotian Z Thompson Mark M Toyodo Hiroo H Toyoda Tetsuro T Valen Elvind E van de Wetering Marc M van den Berg Linda M LM Verado Roberto R Vijayan Dipti D Vorontsov Ilya E IE Wasserman Wyeth W WW Watanabe Shoko S Wells Christine A CA Winteringham Louise N LN Wolvetang Ernst E Wood Emily J EJ Yamaguchi Yoko Y Yamamoto Masayuki M Yoneda Misako M Yonekura Yohei Y Yoshida Shigehiro S Zabierowski Susan E SE Zhang Peter G PG Zhao Xiaobei X Zucchelli Silvia S Summers Kim M KM Suzuki Harukazu H Daub Carsten O CO Kawai Jun J Heutink Peter P Hide Winston W Freeman Tom C TC Lenhard Boris B Bajic Vladimir B VB Taylor Martin S MS Makeev Vsevolod J VJ Sandelin Albin A Hume David A DA Carninci Piero P Hayashizaki Yoshihide Y
Nature 20140301 7493
Regulated transcription controls the diversity, developmental pathways and spatial organization of the hundreds of cell types that make up a mammal. Using single-molecule cDNA sequencing, we mapped transcription start sites (TSSs) and their usage in human and mouse primary cells, cell lines and tissues to produce a comprehensive overview of mammalian gene expression across the human body. We find that few genes are truly 'housekeeping', whereas many mammalian promoters are composite entities com ...[more]
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