Ontology highlight
ABSTRACT:
SUBMITTER: Roadmap Epigenomics Consortium
PROVIDER: S-EPMC4530010 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Nature 20150201 7539
The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To address this need, the NIH Roadmap Epigenomics Consortium generated the largest collection so far of human epigenomes for primary cells and tissues. Here we describe the integrative analysis of 111 reference human epigenomes generated as part of the programme, profiled for histone modification patterns, DNA accessibility, D ...[more]